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KMID : 0359819960250030540
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Journal of Korean Neurosurgical Society
1996 Volume.25 No. 3 p.540 ~ p.543
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BCNU-CDDP Continuous Infusion Chemotherapy in Recurrent Oligodendroglioma
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윤상민
이창훈/이승훈/송재욱/김종현
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Abstract
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Eight patients with recurrent oligodendroglioma were treated with 1.3-bis (2-chloroethyl) nitrosourea(BCNU) and CDDP continuous infusion chemotherapy. They were 5 with benign oligodendrogliomas and 3 with anaplastic oligodendrogliomas. All the
reourrent
tumors had been treated with surgery and radiotherapy. Four patients had already received chemotherapy with ACNU. Seven of them showed response to continuous infusion chemotherapy. The time the response to progression was 15 to 67 weeks. No
severe
complication of the chemotherapy was found. In conclusion. BCNU-CDDP continuous infusion chemotherapy is an effective treatment modality in recurrent oligodendrogliomas.
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